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Dissociation of lipopolysaccharide (LPS)-inducible gene expression in murine macrophages pretreated with smooth LPS versus monophosphoryl lipid A.

Lipopolysaccharide (LPS) and the nontoxic derivative of lipid A, monophosphoryl lipid A (MPL), were employed to assess the relationship between expression of LPS-inducible inflammatory genes and the induction of tolerance to LPS in murine macrophages. Both LPS and MPL induced expression (as assessed...

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Detalhes bibliográficos
Main Authors: Henricson, B E, Manthey, C L, Perera, P Y, Hamilton, T A, Vogel, S N
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280852/
https://ncbi.nlm.nih.gov/pubmed/8388859
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