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A Molecular Dynamics Investigation of Lipid Bilayer Perturbation by PIP(2)
Phosphoinositides like phosphatidylinositol 4,5-bisphosphate (PIP(2)) are negatively charged lipids that play a pivotal role in membrane trafficking, signal transduction, and protein anchoring. We have designed a force field for the PIP(2) headgroup using quantum mechanical methods and characterized...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808495/ https://ncbi.nlm.nih.gov/pubmed/20338845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.063 |
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