Mapping Conformational Transitions in Cyclic AMP Receptor Protein: Crystal Structure and Normal-Mode Analysis of Mycobacterium tuberculosis apo-cAMP Receptor Protein

Cyclic AMP (cAMP) receptor protein, which acts as the sensor of cAMP levels in cells, is a well-studied transcription factor that is best known for allosteric changes effected by the binding of cAMP. Although genetic and biochemical data on the protein are available from several sources, structural...

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Bibliographic Details
Main Authors: Kumar, Pramod, Joshi, Dhananjay C., Akif, Mohd, Akhter, Yusuf, Hasnain, Seyed E., Mande, Shekhar C.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Protein
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808490/
https://ncbi.nlm.nih.gov/pubmed/20338852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.016
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