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Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils

BACKGROUND: Mammalian cells synthesize morphine and the respective biosynthetic pathway has been elucidated. Human neutrophils release this alkaloid into the media after exposure to morphine precursors. However, the exact role of endogenous morphine in inflammatory processes remains unclear. We post...

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Main Authors: Glattard, Elise, Welters, Ingeborg D., Lavaux, Thomas, Muller, Arnaud H., Laux, Alexis, Zhang, Dan, Schmidt, Alexander R., Delalande, François, Laventie, Benoît-Joseph, Dirrig-Grosch, Sylvie, Colin, Didier A., Van Dorsselaer, Alain, Aunis, Dominique, Metz-Boutigue, Marie-Hélène, Schneider, Francis, Goumon, Yannick
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808358/
https://ncbi.nlm.nih.gov/pubmed/20098709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008791
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