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Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils

BACKGROUND: Mammalian cells synthesize morphine and the respective biosynthetic pathway has been elucidated. Human neutrophils release this alkaloid into the media after exposure to morphine precursors. However, the exact role of endogenous morphine in inflammatory processes remains unclear. We post...

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Main Authors: Glattard, Elise, Welters, Ingeborg D., Lavaux, Thomas, Muller, Arnaud H., Laux, Alexis, Zhang, Dan, Schmidt, Alexander R., Delalande, François, Laventie, Benoît-Joseph, Dirrig-Grosch, Sylvie, Colin, Didier A., Van Dorsselaer, Alain, Aunis, Dominique, Metz-Boutigue, Marie-Hélène, Schneider, Francis, Goumon, Yannick
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808358/
https://ncbi.nlm.nih.gov/pubmed/20098709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008791
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