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Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

BACKGROUND: Costimulatory signaling has been implicated as a potential regulator of antitumor immunity in various human cancers. In contrast to the negative prognostic value of aberrant B7-H1 expression by pancreatic cancer cells, the role of B7-H3 is still unknown. Therefore, we investigated the ex...

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Detalhes bibliográficos
Main Authors: Loos, Martin, Hedderich, Dennis M, Ottenhausen, Malte, Giese, Nathalia A, Laschinger, Melanie, Esposito, Irene, Kleeff, Jörg, Friess, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808322/
https://ncbi.nlm.nih.gov/pubmed/20035626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-463
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