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Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties

BACKGROUND: The identification of genetic target genes is a key step for rational engineering of production strains towards bio-based chemicals, fuels or therapeutics. This is often a difficult task, because superior production performance typically requires a combination of multiple targets, whereb...

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Main Authors: Melzer, Guido, Esfandabadi, Manely Eslahpazir, Franco-Lara, Ezequiel, Wittmann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808316/
https://ncbi.nlm.nih.gov/pubmed/20035624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-120
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