In-depth Qualitative and Quantitative Profiling of Tyrosine Phosphorylation Using a Combination of Phosphopeptide Immunoaffinity Purification and Stable Isotope Dimethyl Labeling

Several mass spectrometry-based assays have emerged for the quantitative profiling of cellular tyrosine phosphorylation. Ideally, these methods should reveal the exact sites of tyrosine phosphorylation, be quantitative, and not be cost-prohibitive. The latter is often an issue as typically several m...

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Bibliografski detalji
Glavni autori: Boersema, Paul J., Foong, Leong Yan, Ding, Vanessa M. Y., Lemeer, Simone, van Breukelen, Bas, Philp, Robin, Boekhorst, Jos, Snel, Berend, den Hertog, Jeroen, Choo, Andre B. H., Heck, Albert J. R.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2010
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808269/
https://ncbi.nlm.nih.gov/pubmed/19770167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900291-MCP200
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