In-depth Qualitative and Quantitative Profiling of Tyrosine Phosphorylation Using a Combination of Phosphopeptide Immunoaffinity Purification and Stable Isotope Dimethyl Labeling

Several mass spectrometry-based assays have emerged for the quantitative profiling of cellular tyrosine phosphorylation. Ideally, these methods should reveal the exact sites of tyrosine phosphorylation, be quantitative, and not be cost-prohibitive. The latter is often an issue as typically several m...

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Main Authors: Boersema, Paul J., Foong, Leong Yan, Ding, Vanessa M. Y., Lemeer, Simone, van Breukelen, Bas, Philp, Robin, Boekhorst, Jos, Snel, Berend, den Hertog, Jeroen, Choo, Andre B. H., Heck, Albert J. R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808269/
https://ncbi.nlm.nih.gov/pubmed/19770167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900291-MCP200
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