High Content Screening for Inhibitors of Protein Interactions and Post-translational Modifications in Primary Cells by Proximity Ligation

The cost of developing new drugs is a major obstacle for pharmaceutical companies and academia with many drugs identified in the drug discovery process failing approval for clinical use due to lack of intended effect or because of severe side effects. Since the early 1990s, high throughput screening...

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Bibliographic Details
Main Authors: Leuchowius, Karl-Johan, Jarvius, Malin, Wickström, Malin, Rickardson, Linda, Landegren, Ulf, Larsson, Rolf, Söderberg, Ola, Fryknäs, Mårten, Jarvius, Jonas
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808263/
https://ncbi.nlm.nih.gov/pubmed/19864249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900331-MCP200
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