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Proteome, Phosphoproteome, and Hydroxyproteome of Liver Mitochondria in Diabetic Rats at Early Pathogenic Stages

It has been proposed that mitochondrial dysfunction is involved in the pathogenesis of type 2 diabetes (T2D). To dissect the underlying mechanisms, we performed a multiplexed proteomics study on liver mitochondria isolated from a spontaneous diabetic rat model before/after they were rendered diabeti...

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Detalhes bibliográficos
Main Authors: Deng, Wen-Jun, Nie, Song, Dai, Jie, Wu, Jia-Rui, Zeng, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808256/
https://ncbi.nlm.nih.gov/pubmed/19700791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900020-MCP200
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