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Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Molecule Imaging: Evidence That the Spindle Environment Does Not Stabilize Microtubules

Metaphase spindles are steady-state ensembles of microtubules that turn over rapidly and slide poleward in some systems. Since the discovery of dynamic instability in the mid-1980s, models for spindle morphogenesis have proposed that microtubules are stabilized by the spindle environment. We used si...

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Main Authors: Needleman, Daniel J., Groen, Aaron, Ohi, Ryoma, Maresca, Tom, Mirny, Leonid, Mitchison, Tim
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808228/
https://ncbi.nlm.nih.gov/pubmed/19940016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0816
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