Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

PURPOSE: Interleukin-7 has critical and non redundant roles in T-cell development, hematopoiesis and post developmental immune functions as a prototypic homeostatic cytokine. Based on a large body of pre-clinical evidence, it may have multiple therapeutic applications in immunodeficiency states, eit...

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Autores principales: Sportès, Claude, Babb, Rebecca R., Krumlauf, Michael C., Hakim, Frances T., Steinberg, Seth M., Chow, Catherine K., Brown, Margaret R., Fleisher, Thomas A., Noel, Pierre, Maric, Irina, Stetler-Stevenson, Maryalice, Engel, Julie, Buffet, Renaud, Morre, Michel, Amato, Robert J, Pecora, Andrew, Mackall, Crystal L., Gress, Ronald E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808195/
https://ncbi.nlm.nih.gov/pubmed/20068111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1303
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