Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-κB and Prox1

The concept of inflammation-induced lymphangiogenesis (ie, formation of new lymphatic vessels) has long been recognized, but the molecular mechanisms remained largely unknown. The 2 primary mediators of lymphangiogenesis are vascular endothelial growth factor receptor-3 (VEGFR-3) and Prox1. The key...

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Bibliografiske detaljer
Main Authors: Flister, Michael J., Wilber, Andrew, Hall, Kelly L., Iwata, Caname, Miyazono, Kohei, Nisato, Riccardo E., Pepper, Michael S., Zawieja, David C., Ran, Sophia
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Vascular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808162/
https://ncbi.nlm.nih.gov/pubmed/19901262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196840
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