CD94 surface density identifies a functional intermediary between the CD56(bright) and CD56(dim) human NK-cell subsets

Human CD56(bright) natural killer (NK) cells possess little or no killer immunoglobulin-like receptors (KIRs), high interferon-γ (IFN-γ) production, but little cytotoxicity. CD56(dim) NK cells have high KIR expression, produce little IFN-γ, yet display high cytotoxicity. We hypothesized that, if hum...

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Hauptverfasser: Yu, Jianhua, Mao, Hsiaoyin C., Wei, Min, Hughes, Tiffany, Zhang, Jianying, Park, Il-kyoo, Liu, Shujun, McClory, Susan, Marcucci, Guido, Trotta, Rossana, Caligiuri, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808153/
https://ncbi.nlm.nih.gov/pubmed/19897577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-215491
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