Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4

During inflammation, elevated granulocyte macrophage–colony-stimulating factor (GM-CSF) directs the development of new dendritic cells (DCs). This pathway is influenced by environmental factors, and we previously showed that physiologic levels of estradiol, acting through estrogen receptor alpha (ER...

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Autors principals: Carreras, Esther, Turner, Sean, Frank, Mark Barton, Knowlton, Nicholas, Osban, Jeanette, Centola, Michael, Park, Chae Gyu, Simmons, Amie, Alberola-Ila, José, Kovats, Susan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808152/
https://ncbi.nlm.nih.gov/pubmed/19880499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236935
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