Roles of Interleukin-6 and Parathyroid Hormone-Related Peptide in Osteoclast Formation Associated with Oral Cancers : Significance of Interleukin-6 Synthesized by Stromal Cells in Response to Cancer Cells

We investigated the roles of interleukin-6 (IL-6) and parathyroid hormone-related peptide (PTHrP) in oral squamous cell carcinoma (OSCC)-induced osteoclast formation. Microarray analyses performed on 43 human OSCC specimens revealed that many of the specimens overexpressed PTHrP mRNA, but a few over...

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Detalhes bibliográficos
Main Authors: Kayamori, Kou, Sakamoto, Kei, Nakashima, Tomoki, Takayanagi, Hiroshi, Morita, Kei-ichi, Omura, Ken, Nguyen, Su Tien, Miki, Yoshio, Iimura, Tadahiro, Himeno, Akiko, Akashi, Takumi, Yamada-Okabe, Hisafumi, Ogata, Etsuro, Yamaguchi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808100/
https://ncbi.nlm.nih.gov/pubmed/20035059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090299
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