Blockade of Autoantibody-Initiated Tissue Damage by Using Recombinant Fab Antibody Fragments against Pathogenic Autoantigen

Activation of the complement cascade via the classical pathway is required for the development of tissue injury in many autoantibody-mediated diseases. It therefore makes sense to block the pathological action of autoantibodies by preventing complement activation through inhibition of autoantibody b...

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Autors principals: Wang, Gang, Ujiie, Hideyuki, Shibaki, Akihiko, Nishie, Wataru, Tateishi, Yasuki, Kikuchi, Kazuhiro, Li, Qiang, McMillan, James R., Morioka, Hiroshi, Sawamura, Daisuke, Nakamura, Hideki, Shimizu, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808096/
https://ncbi.nlm.nih.gov/pubmed/20042683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090744
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