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An Efficient Boric Acid Mediated Preparation of α-Hydroxyamides

An efficient methodology for the preparation of α-hydroxyamides via boric acid mediated addition of isonitriles on to aldehydes has been developed. The reaction of isonitriles with α-boronobenzaldehyde takes place under intramolecular catalysis conditions to provide functionalized benzoxaboroles.

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Detalhes bibliográficos
Main Authors: Kumar, J. Sravan, Jonnalagadda, Subash C., Mereddy, Venkatram R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808032/
https://ncbi.nlm.nih.gov/pubmed/20161580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.12.008
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