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Induction of early gene expression in murine macrophages by synthetic lipid A analogs with differing endotoxic potentials.

Numerous lipid A analogs have been synthesized in an attempt to dissociate endotoxic activities from beneficial immunomodulatory activities. In the present study, we have evaluated select lipid A analogs in macrophages for their ability to induce a panel of lipopolysaccharide (LPS)-inducible genes t...

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Autors principals: Perera, P Y, Manthey, C L, Stütz, P L, Hildebrandt, J, Vogel, S N
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC280797/
https://ncbi.nlm.nih.gov/pubmed/7683001
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