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Heparanase and hepatocellular carcinoma: Promoter or inhibitor?

Heparan sulphate proteoglycans (HSPGs) consist of a core protein and several heparan sulphate (HS) side chains covalently linked. HS also binds a great deal of growth factors, chemokines, cytokines and enzymes to the extracellular matrix and cell surface. Heparanase can specially cleave HS side chai...

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Detalhes bibliográficos
Main Authors: Dong, Shuo, Wu, Xiong-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807950/
https://ncbi.nlm.nih.gov/pubmed/20082475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i3.306
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