Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias

We have described a severe combined immunodeficiency (SCID) mouse model that permits the subcutaneous growth of primary human acute leukemia blast cells into a measurable subcutaneous nodule which may be followed by the development of disseminated disease. Utilizing the SCID mouse model, we examined...

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Detalhes bibliográficos
Main Authors: Yan, Ying, Wieman, Eric A, Guan, Xiuqin, Jakubowski, Ann A, Steinherz, Peter G, O'Reilly, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807866/
https://ncbi.nlm.nih.gov/pubmed/20040095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-2-51
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