Tetrahdroxysqualene from Rhus taitensis Shows Antimycobacterial Activity Against Mycobacterium tuberculosis

Tuberculosis has become a major health problem, in particular with the emergence of extremely drug resistant tuberculosis (XDRTB). In our search for new therapeutic leads against TB, we isolated a new triterpene (1) from the plant Rhus taitensis collected in Papua New Guinea. Tetrahydroxysqualene (1...

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Bibliographic Details
Main Authors: Noro, Jeffrey C., Barrows, Louis R., Gideon, Osia G., Ireland, Chris M., Koch, Michael, Matainaho, Teatulohi, Piskaut, Pius, Pond, Christopher D., Bugni, Tim S.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807728/
https://ncbi.nlm.nih.gov/pubmed/18710283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800082e
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