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Establishment of an antitoxoplasma state by stable expression of mouse indoleamine 2,3-dioxygenase.

Indoleamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme, is inducible by various interferons (IFNs). IDO-mediated tryptophan degradation, but not the formation of IDO-catalyzed tryptophan metabolites, has been suggested as a mechanism for the antiparasitic action of IFN-gamma. To determine...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Habara-Ohkubo, A, Shirahata, T, Takikawa, O, Yoshida, R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8478070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.5.1810-1813.1993
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