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Long term potentiation depends on release of D-serine from astrocytes

Long-term potentiation (LTP) of synaptic transmission provides an experimental model for studying mechanisms of memory1. The classical form of LTP relies on N-methyl-D-aspartate receptors (NMDARs), and it has emerged that astroglia can regulate their activation through Ca(2+)-dependent release of th...

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Bibliographic Details
Main Authors: Henneberger, Christian, Papouin, Thomas, Oliet, Stéphane H. R., Rusakov, Dmitri A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807667/
https://ncbi.nlm.nih.gov/pubmed/20075918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08673
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