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Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement

Many biological macromolecular interactions proceed via lowly-populated, highly transient species that arise from rare excursions between the minimum free energy configuration and other local minima of the free energy landscape. Little is known about the structural properties of such lowly-occupied...

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Autore principale: Clore, G. Marius
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807640/
https://ncbi.nlm.nih.gov/pubmed/18931781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b810232e
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