Cooperative action of CD8 T lymphocytes and natural killer cells controls tumour growth under conditions of restricted T-cell receptor diversity

In mice expressing a transgenic T-cell receptor (TCR; TCRP1A) of DBA/2 origin with reactivity towards a cancer-germline antigen P1A, the number of TCRP1A CD8(+) T cells in lymphoid organs is lower in DBA/2 than in B10.D2 or B10.D2(× DBA/2)F(1) mice. This reduction results from haemopoietic cell auto...

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Hlavní autoři: Shanker, Anil, Buferne, Michel, Schmitt-Verhulst, Anne-Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807485/
https://ncbi.nlm.nih.gov/pubmed/20050329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03150.x
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