Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome

BACKGROUND: Host defense peptides are a critical component of the innate immune system. Human alpha- and beta-defensin genes are subject to copy number variation (CNV) and historically the organization of mouse alpha-defensin genes has been poorly defined. Here we present the first full manual genom...

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Main Authors: Amid, Clara, Rehaume, Linda M, Brown, Kelly L, Gilbert, James GR, Dougan, Gordon, Hancock, Robert EW, Harrow, Jennifer L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807441/
https://ncbi.nlm.nih.gov/pubmed/20003482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-606
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