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Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics

BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regulation of cellular growth and development. While highly studied, it is still not fully understood how the signal is orchestrated. One of the reasons for the complexity of this pathway is the extensive n...

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Detalhes bibliográficos
Main Authors: Wang, Dennis YQ, Cardelli, Luca, Phillips, Andrew, Piterman, Nir, Fisher, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807436/
https://ncbi.nlm.nih.gov/pubmed/20028552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-118
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