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Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl

The interaction of Abl-Src homology 3 domain (SH3) with the high affinity peptide p41 is the most notable example of the inconsistency existing between the currently accepted description of SH3 complexes and their binding thermodynamic signature. We had previously hypothesized that the presence of i...

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Main Authors: Palencia, Andres, Camara-Artigas, Ana, Pisabarro, M. Teresa, Martinez, Jose C., Luque, Irene
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807336/
https://ncbi.nlm.nih.gov/pubmed/19906645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048033
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