Molecular Basis for Association of PIPKIγ-p90 with Clathrin Adaptor AP-2

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is an essential determinant in clathrin-mediated endocytosis (CME). In mammals three type I phosphatidylinositol-4-phosphate 5-kinase (PIPK) enzymes are expressed, with the Iγ-p90 isoform being highly expressed in the brain where it regulates synap...

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Bibliographic Details
Main Authors: Kahlfeldt, Nina, Vahedi-Faridi, Ardeschir, Koo, Seong Joo, Schäfer, Johannes G., Krainer, Georg, Keller, Sandro, Saenger, Wolfram, Krauss, Michael, Haucke, Volker
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Molecular Basis of Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807329/
https://ncbi.nlm.nih.gov/pubmed/19903820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074906
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