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Characterization of the Mycobacterial AdnAB DNA Motor Provides Insights into the Evolution of Bacterial Motor-Nuclease Machines

Mycobacterial AdnAB exemplifies a family of heterodimeric motor-nucleases involved in processing DNA double strand breaks (DSBs). The AdnA and AdnB subunits are each composed of an N-terminal UvrD-like motor domain and a C-terminal RecB-like nuclease module. Here we conducted a biochemical character...

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Sonraí Bibleagrafaíochta
Main Authors: Unciuleac, Mihaela-Carmen, Shuman, Stewart
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807320/
https://ncbi.nlm.nih.gov/pubmed/19920138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.076133
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