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Regulation of SIV(mac)239 Basal Long Terminal Repeat Activity and Viral Replication in Macrophages: FUNCTIONAL ROLES OF TWO CCAAT/ENHANCER-BINDING PROTEIN β SITES IN ACTIVATION AND INTERFERON β-MEDIATED SUPPRESSION

CCAAT/enhancer-binding protein (C/EBP) β and C/EBP sites in the HIV-1 long terminal repeat (LTR) are crucial for HIV-1 replication in monocyte/macrophages and for the ability of interferon β (IFNβ) to inhibit ongoing active HIV replication in these cells. This IFNβ-mediated down-regulation involves...

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Hlavní autoři: Ravimohan, Shruthi, Gama, Lucio, Barber, Sheila A., Clements, Janice E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807283/
https://ncbi.nlm.nih.gov/pubmed/19933495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.075929
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