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Reduced growth, abnormal kidney structure, and type 2 (AT(2)) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT(1A) and AT(1B) receptors for angiotensin II

The classically recognized functions of the renin–angiotensin system are mediated by type 1 (AT(1)) angiotensin receptors. Whereas man possesses a single AT(1) receptor, there are two AT(1) receptor isoforms in rodents (AT(1A) and AT(1B)) that are products of separate genes (Agtr1a and Agtr1b). We h...

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Hlavní autoři: Oliverio, Michael I., Kim, Hyung-Suk, Ito, Masaki, Le, Thu, Audoly, Laurent, Best, Christopher F., Hiller, Sylvia, Kluckman, Kimberly, Maeda, Nobuyo, Smithies, Oliver, Coffman, Thomas M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC28071/
https://ncbi.nlm.nih.gov/pubmed/9860997
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