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Immunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implications

BACKGROUND: HER-2/neu and c-kit (CD117) onco-protein are increasingly being recognized as targets for therapy in solid tumors, but data on their role in malignant melanoma is currently limited. We studied the prevalence of overexpression of HER-2/neu and c-Kit in 202 patients with malignant melanoma...

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Autors principals: Potti, Anil, Hille, Rachel C, Koch, Michael
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC280698/
https://ncbi.nlm.nih.gov/pubmed/14617373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-2-8
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