A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases

BACKGROUND: Tripeptidyl-peptidase I, also known as CLN2, is a member of the family of sedolisins (serine-carboxyl peptidases). In humans, defects in expression of this enzyme lead to a fatal neurodegenerative disease, classical late-infantile neuronal ceroid lipofuscinosis. Similar enzymes have been...

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Hlavní autoři: Wlodawer, Alexander, Durell, Stewart R, Li, Mi, Oyama, Hiroshi, Oda, Kohei, Dunn, Ben M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2003
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC280685/
https://ncbi.nlm.nih.gov/pubmed/14609438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-3-8
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