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Human CD4(+) Memory T Cells Can Become CD4(+)IL-9(+) T Cells

BACKGROUND: IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-β directs mouse CD4(+)CD25(−)CD62L(+) T cells to commit to inflammatory IL-9 producing CD4(+) T cells. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that human inducible r...

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Detalhes bibliográficos
Main Authors: Putheti, Prabhakar, Awasthi, Amit, Popoola, Joyce, Gao, Wenda, Strom, Terry B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806834/
https://ncbi.nlm.nih.gov/pubmed/20090929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008706
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