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Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

Faithful transmission of genetic material to daughter cells involves a characteristic temporal order of DNA replication, which may play a significant role in the inheritance of epigenetic states. We developed a genome-scale approach—Repli Seq—to map temporally ordered replicating DNA using massively...

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Autori principali: Hansen, R. Scott, Thomas, Sean, Sandstrom, Richard, Canfield, Theresa K., Thurman, Robert E., Weaver, Molly, Dorschner, Michael O., Gartler, Stanley M., Stamatoyannopoulos, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806781/
https://ncbi.nlm.nih.gov/pubmed/19966280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912402107
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