Dopamine/adenosine interactions related to locomotion and tremor in animal models: Possible relevance to parkinsonism

Adenosine A(2A) antagonists can exert antiparkinsonian effects in animal models. Recent experiments studied the ability of MSX-3 (an adenosine A(2A) antagonist) to reverse the locomotor suppression and tremor produced by dopamine antagonists in rats. MSX-3 reversed haloperidol-induced suppression of...

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Autors principals: Salamone, John D., Ishiwari, Keita, Betz, Adrienne J., Farrar, Andrew M., Mingote, Susana M., Font, Laura, Hockemeyer, Jörg, Müller, Christa E., Correa, Mercè
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806674/
https://ncbi.nlm.nih.gov/pubmed/18585081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2008.04.017
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