The glycosaminoglycan-binding domain of PRELP acts as a cell type–specific NF-κB inhibitor that impairs osteoclastogenesis

Proline/arginine-rich end leucine-rich repeat protein (PRELP) is a glycosaminoglycan (GAG)- and collagen-binding anchor protein highly expressed in cartilage, basement membranes, and developing bone. We observed that PRELP inhibited in vitro and in vivo mouse osteoclastogenesis through its GAG-bindi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rucci, Nadia, Rufo, Anna, Alamanou, Marina, Capulli, Mattia, Del Fattore, Andrea, Åhrman, Emma, Capece, Daria, Iansante, Valeria, Zazzeroni, Francesca, Alesse, Edoardo, Heinegård, Dick, Teti, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806584/
https://ncbi.nlm.nih.gov/pubmed/19951916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados