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The “Glutamate Switch” : a link between ATPase activity and ligand binding in AAA+ proteins

AAA+ proteins carry out diverse functions in cells. In most cases, their ATPase activity is very tightly regulated by protein partners and target ligands but the mechanism for this control has remained unclear. We have identified a conserved link between the ligand binding and ATPase sites in AAA+ p...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaodong, Wigley, Dale B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806578/
https://ncbi.nlm.nih.gov/pubmed/18849995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1501
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