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Rrp17p Is a Eukaryotic Exonuclease Required for 5′ End Processing of Pre-60S Ribosomal RNA

Ribosomal processing requires a series of endo- and exonucleolytic steps for the production of mature ribosomes, of which most have been described. To ensure ribosome synthesis, 3′ end formation of rRNA uses multiple nucleases acting in parallel; however, a similar parallel mechanism had not been de...

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Autors principals: Oeffinger, Marlene, Zenklusen, Daniel, Ferguson, Angelica, Wei, Karen E., El Hage, Aziz, Tollervey, David, Chait, Brian T., Singer, Robert H., Rout, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806520/
https://ncbi.nlm.nih.gov/pubmed/20005841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.11.011
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