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Calcineurin activates interleukin-6 transcription in mouse skeletal muscle in vivo and in C(2)C(12) myotubes in vitro

Expression of the cytokine interleukin-6 (IL-6) by skeletal muscle is hugely increased in response to a single bout of endurance exercise, and this appears to be mediated by increases in intracellular calcium. We examined the effects of endurance exercise on IL-6 mRNA levels and promoter activity in...

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Autors principals: Allen, David L., Uyenishi, Jill J., Cleary, Allison S., Mehan, Ryan S., Lindsay, Sarah F., Reed, Jason M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806210/
https://ncbi.nlm.nih.gov/pubmed/19907005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00325.2009
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