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A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury

Several studies have recently demonstrated that G protein-coupled receptor 30 (GPER) can directly bind to estrogen and mediate its action. We investigated the role and the mechanism of estrogen-induced cardioprotection after ischemia-reperfusion using a specific GPER agonist G1. Isolated hearts from...

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書誌詳細
主要な著者: Bopassa, Jean Chrisostome, Eghbali, Mansoureh, Toro, Ligia, Stefani, Enrico
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806134/
https://ncbi.nlm.nih.gov/pubmed/19880667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00588.2009
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