Major role for ACE-independent intrarenal ANG II formation in type II diabetes

Combination therapy of angiotensin-converting enzyme (ACE) inhibition and AT(1) receptor blockade has been shown to provide greater renoprotection than ACE inhibitor alone in human diabetic nephropathy, suggesting that ACE-independent pathways for ANG II formation are of major significance in diseas...

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Autors principals: Park, Sungmi, Bivona, Benjamin J., Kobori, Hiroyuki, Seth, Dale M., Chappell, Mark C., Lazartigues, Eric, Harrison-Bernard, Lisa M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
Matèries:
Editorial Focus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806123/
https://ncbi.nlm.nih.gov/pubmed/19846569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00519.2009
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