Novel canine models of obese prediabetes and mild type 2 diabetes

Human type 2 diabetes mellitus (T2DM) is often characterized by obesity-associated insulin resistance (IR) and β-cell function deficiency. Development of relevant large animal models to study T2DM is important and timely, because most existing models have dramatic reductions in pancreatic function a...

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Hauptverfasser: Ionut, Viorica, Liu, Huiwen, Mooradian, Vahe, Castro, Ana Valeria B., Kabir, Morvarid, Stefanovski, Darko, Zheng, Dan, Kirkman, Erlinda L., Bergman, Richard N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806110/
https://ncbi.nlm.nih.gov/pubmed/19843874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00466.2009
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