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Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto

Transforming growth factor β (TGF-β) signals regulate multiple processes during development and in adult. We recently showed that tomoregulin-1 (TMEFF1), a transmembrane protein, selectively inhibits nodal but not activin in early Xenopus embryos. Here we report that TMEFF1 binds to the nodal corece...

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Detalhes bibliográficos
Main Authors: Harms, Paul W., Chang, Chenbei
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280611/
https://ncbi.nlm.nih.gov/pubmed/14563676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1127703
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