Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity

Werner syndrome is a premature aging disease caused by loss of function mutations in the Werner syndrome protein (WRN) gene. WRN is a RecQ helicase that in contrast to every other member of this family of proteins possesses an exonuclease activity. The findings that cells lacking WRN activity displa...

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Hlavní autoři: Li, Baomin, Reddy, Sita, Comai, Lucio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806009/
https://ncbi.nlm.nih.gov/pubmed/20157518
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