Ascorbic Acid Potentiation of Arsenic Trioxide Anticancer Activity Against Acute Promyelocytic Leukemia

INTRODUCTION: Acute promyelocytic leukemia (APL) is a malignant disorder of the white blood cells. Arsenic trioxide (As(2)O(3)) has been used as a therapeutic agent to treat APL and other tumors. Studies suggest that ascorbic acid (AA) supplementation may improve the clinical outcome of As(2)O(3) fo...

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Main Authors: Yedjou, Clement, Thuisseu, Laurette, Tchounwou, Christine, Gomes, Maria, Howard, Carolyn, Tchounwou, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805867/
https://ncbi.nlm.nih.gov/pubmed/20098508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2009.00022.x
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