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Influence of Genetic Background on Genetically Engineered Mouse Phenotypes

The history of mouse genetics, which involves the study of strain-dependent phenotype variability, makes it clear that the genetic background onto which a gene-targeted allele is placed can cause considerable variation in genetically engineered mouse (GEM) phenotype. This variation can present itsel...

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Detalhes bibliográficos
Autor principal: Doetschman, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805848/
https://ncbi.nlm.nih.gov/pubmed/19266333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-471-1_23
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