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Hereditary thrombocytosis caused by MPL(Ser505Asn) is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis
BACKGROUND: The MPL(Ser505Asn) mutation has been reported to be a cause of hereditary thrombocythemia. Recently, we detected this mutation in a large proportion of children with familial thrombocythemia, suggesting that in Italy the incidence of MPL(Ser505Asn) mutation could be underestimated. DESIG...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ferrata Storti Foundation
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805752/ https://ncbi.nlm.nih.gov/pubmed/19713221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007542 |
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