Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults

BACKGROUND: Molecular lesions in T-cell acute lymphoblastic leukemias affect regulators of cell cycle, proliferation, differentiation, survival and apoptosis in multi-step pathogenic pathways. Full genetic characterization is needed to identify events concurring in the development of these leukemias...

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Main Authors: Gorello, Paolo, La Starza, Roberta, Varasano, Emanuela, Chiaretti, Sabina, Elia, Loredana, Pierini, Valentina, Barba, Gianluca, Brandimarte, Lucia, Crescenzi, Barbara, Vitale, Antonella, Messina, Monica, Grammatico, Sara, Mancini, Marco, Matteucci, Caterina, Bardi, Antonella, Guarini, Anna, Martelli, Massimo Fabrizio, Foà, Robin, Mecucci, Cristina
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805748/
https://ncbi.nlm.nih.gov/pubmed/20065082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.010413
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